He went through with his plan although all his friends advised him to abandon it.
after all 毕竟；终究
After all, no one knows me better than me.
in spite of… 尽管；不管，不顾
In spite of the material benefits wealth provides, I believe one should abandon the pursuit of materialism and instead concentrate on the pursuit of happiness.
Despite their efforts the project collapsed.
even if 即使
Even if we cannot slow down every day, at least slow down on Sunday.
even though 虽然
Even though we may have a hundred and one things in our to-do list, not all of them have the same importance.
Though he had a good start, I rowed him down at last.
Admittedly, it is a huge challenge for many people,but it is a fact of working life.
whatever may happen 无论发生什么事
Whatever may happen, we are determined to do this work.